标题：Oxidized cellulose-based hemostatic materials
作者：Zhang, Shaohua; Li, Jiwei; Chen, Shaojuan; Zhang, Xiying; Ma, Jianwei; He, Jinmei
作者机构：[Li, Jiwei; Chen, Shaojuan; Ma, Jianwei] Qingdao Univ, Coll Text & Clothing, Ind Res Inst Nonwovens & Tech Text, Qingdao 266071, Shandong, Peoples R C 更多
通讯作者：Li, Jiwei;Li, JW;He, JM
通讯作者地址：[Li, JW]Qingdao Univ, Coll Text & Clothing, Ind Res Inst Nonwovens & Tech Text, Qingdao 266071, Shandong, Peoples R China;[He, JM]Harbin Inst Technol, 更多
关键词：Oxidized cellulose; Hemostatic materials; Antibacterial activity;; Biodegradability
摘要：The application of hemostatic agents is essential to prevent significant blood loss and death from excessive bleeding in surgical or emergency scenarios. Oxidized cellulose is an excellent biodegradable and biocompatible derivate of cellulose, which has become one of the most important hemostatic agents used in surgical procedures. However, to date, there has been no comprehensive report assessing oxidized cellulose-based hemostatic materials. Hence, this paper first reviewed the oxidation preparation, cellulose origin and structure, as well as biodegradability and safety of oxidized cellulose. Then a comprehensive review regarding the hemostatic mechanisms, various forms, modification, and current commercially available products of oxidized cellulose is discussed, which emphatically presents the most significant developments in the recent scientific literature. In conclusion, this paper summarizes the latest developments in oxidized cellulose-based hemostatic materials and provides a reference for further research and development in this field.