标题：Long-term outcomes of minimally invasive Ivor Lewis esophagostomy for esophageal squamous cell carcinoma: Compared with open approach
作者：Zhang, Zhenghua; Xu, Meiqing; Guo, Mingfa; Liu, Xuegang
作者机构：[Zhang, Zhenghua] Shandong Univ, 17923 Jingshi Rd, Jinan 250000, Shandong, Peoples R China.; [Xu, Meiqing; Guo, Mingfa] Anhui Prov Hosp, Dept Thorac 更多
通讯作者地址：[Liu, XG]Bengbu Med Coll, Dept Thorac Surg, Affiliated Hosp 1, 287 Changhuai Rd, Bengbu 233000, Anhui, Peoples R China.
来源：INTERNATIONAL JOURNAL OF SURGERY
关键词：Esophageal squamous cell carcinoma; Thoracoscopy; Laparoscopy; Ivor; Lewis esophagostomy
摘要：Objective: To investigate the safety and long-term efficacy of combined thoraco-laparoscopic minimally invasive Ivor Lewis esophagostomy(MI-ILE) in the treatment of esophageal squamous cell carcinoma.; Methods: The clinical data of patients with esophageal squamous cell carcinoma who underwent Ivor Lewis esophagostomy of esophageal cancer from October 2011 to June 2013 were retrospectively analyzed. Of which 90 patients received MI-ILE, 95 patients underwent open Ivor Lewis esophagostomy (O-ILE). The clinicopathological features, intraoperative records and incidences of postoperative complications of the two groups were compared with t-test and x(2) test. The primary end point of the study was 3-year disease-free survival (DFS) and 3-year overall survival (OS) was a secondary end point.; Results: There were no statistically significant differences in gender, age, preoperative comorbidities, American Society of Anesthesiologists score and position of the tumor between the two groups. There was also no significant difference in clinicopathological characteristics, operation time, length of tumor resection margin and number of resected lymph nodes between the two groups (P > 0.05). In MI-ILE group, the blood loss was lower than in the O-ILE group [(159.1 + 97.4) ml vs. (191.7 + 141.9) ml, t = 1.811, P = 1.811] and the postoperative hospital stay was shorter [(11.5 + 4.5) d vs. (13.9 + 6.2) d, t = 2.944, P = 0.004]. There was no significant difference in the incidences of perioperative mortality and major morbidities (P > 0.05). Minor complications including incision infection rate (1.1% vs 8.4%, x(2) = 3.873, P = 0.049) and pulmonary infection incidence (3.3% vs 11.57%, x(2) = 4.492, P = 0.034) is lower in MIILE group. There was no significant difference in 3-year disease-free survival (DFS) and 3-year overall survival (OS) between the two groups.; Conclusion: MI-ILE is a technically safe and feasible approach for esophageal squamous cell carcinoma treatment. The oncologic outcomes of MI-ILE are comparable to that of O-ILE 3 years after resection. (C) 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.