标题:Vitamin E: supplement versus diet in neurodegenerative diseases
作者:Shen, Liang; Ji, Hong-Fang
作者机构:[Shen, Liang; Ji, Hong-Fang] Shandong Univ Technol, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China.
通讯作者:Shen, L
通讯作者地址:[Shen, L]Shandong Univ Technol, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China.
来源:TRENDS IN MOLECULAR MEDICINE
出版年:2012
卷:18
期:8
页码:443-445
DOI:10.1016/j.molmed.2012.04.010
摘要:Contradicting outcomes have been observed in numerous studies investigating the benefits of vitamin E supplements in the context of neurodegenerative diseases. By reviewing epidemiological studies and clinical trials, it is found that dietary intake of vitamin E exhibits beneficial effects on neurodegeneration, whereas alpha-tocopherol supplements failed in most interventional trials. Potential reasons for why alpha-tocopherol supplements exhibit disappointing effects, especially compared with dietary intake, are put forward and implications for future studies are discussed.
收录类别:SCIE
WOS核心被引频次:7
资源类型:期刊论文
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