标题:Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors
作者:Jing, Lanlan; Wu, Gaochan; Kang, Dongwei; Zhou, Zhongxia; Song, Yuning; Liu, Xinyong; Zhan, Peng
作者机构:[Jing, Lanlan; Wu, Gaochan; Kang, Dongwei; Zhou, Zhongxia; Liu, Xinyong; Zhan, Peng] Shandong Univ, Sch Pharmaceut Sci, Dept Med Chem, Key Lab Chem Bi 更多
通讯作者:Liu, XY;Zhan, P
通讯作者地址:[Liu, XY; Zhan, P]Shandong Univ, Sch Pharmaceut Sci, Dept Med Chem, Key Lab Chem Biol,Minist Educ, 44 West Culture Rd, Jinan 250012, Shandong, Peoples 更多
来源:DRUG DISCOVERY TODAY
出版年:2019
卷:24
期:2
页码:629-635
DOI:10.1016/j.drudis.2018.11.012
摘要:Butyrylcholinesterase (BChE) is considered a promising drug target for the treatment of moderate to severe Alzheimer's disease (AD). Here, we review medicinal -chemistry strategies that are currently available for the discovery of selective BChE inhibitors.
收录类别:SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057972092&doi=10.1016%2fj.drudis.2018.11.012&partnerID=40&md5=af43fbbba7ba055f9ace930aced9e2b7
TOP