标题：In vitro degradation and apatite formation of magnesium and zinc incorporated calcium silicate prepared by sol-gel method
作者：Ma J.; Wang C.Z.; Huang B.X.; Zhao X.C.; Chen C.Z.; Yu H.J.
作者机构：[Ma, J] School of Materials Science and Engineering, Liaocheng University, Liaocheng, Shandong, China, Shenzhen Research Institute of Shandong Univers 更多
通讯作者地址：[Ma, J] Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, School of Materials Science and Engin 更多
关键词：bioactivity; Ca2MgSi2O7; Ca2ZnSi2O7; degradability; Sol-gel method
摘要：The high degradation rate limits the clinical applications of calcium silicate bioceramics. In this paper, Ca2MgSi2O7 and Ca2ZnSi2O7 were successfully prepared using sol-gel method by incorporating magnesium and zinc into Ca–Si-based system. The results showed that the obtained ceramics presented the macroporous structure and the incorporation of zinc obviously reduced the samples specific surface area. Compared with CaSiO3 (24.8%), the weight loss of Ca2ZnSi2O7 was the lowest (8.4%) and Ca2MgSi2O7 was the middle (12.1%) after 28 days soaking in Tris-HCl buffers. Meanwhile, the formation of apatite was also confirmed after soaking in SBF. Through above investigations, the incorporation of magnesium and zinc should be one of the effective ways to adjust the degradation and apatite formation of Ca–Si-based bioceramics, which would meet the various clinical demands. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.