标题：1,2,3-triazole bound Au(I) (TA-Au) as chemoselective catalysts in promoting asymmetric synthesis of substituted allenes
作者：Wang, D.;Gautam, L.N.S.;Bollinger, C.;Harris, A.;Li, M.;Shi, X.
作者机构：[Wang, D] C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506, United States;[ Gautam, L.N.S] C. Eugene Bennett 更多
通讯作者地址：[Shi, XD]W Virginia Univ, C Eugene Bennett Dept Chem, Morgantown, WV 26506 USA.
摘要：The triazole-Au (TA-Au) complexes were identified as effective chemoselective catalysts in promoting propargyl ester/ether 3,3-rearrangements. The highly reactive allenes, which could not be isolated by simple cationic gold catalysts, were prepared in excellent yields (1% catalyst loading, >90% yields). Unlike other reported Au catalysts, the TA-Au provided effective chirality transfer without racemization over a long period of time, giving enantioenriched allenes with excellent stereoselectivity (1% catalyst loading, up to 99% ee).