标题:A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria
作者:Tang, Bai-Lu; Yang, Jie; Chen, Xiu-Lan; Wang, Peng; Zhao, Hui-Lin; Su, Hai-Nan; Li, Chun-Yang; Yu, Yang; Zhong, Shuai; Wang, Lei; 更多
作者机构:[Tang, Bai-Lu; Yang, Jie; Chen, Xiu-Lan; Wang, Peng; Zhao, Hui-Lin; Su, Hai-Nan; Yu, Yang; Zhong, Shuai; Wang, Lei; Zhang, Xi-Ying; Zhang, Yu-Zhong] S 更多
通讯作者:Zhang, YZ;Zhang, YZ;Zhang, YZ
通讯作者地址:[Zhang, YZ]Shandong Univ, Marine Biotechnol Res Ctr, State Key Lab Microbial Technol, Qingdao 266237, Peoples R China;[Zhang, YZ]Ocean Univ China, Ins 更多
来源:NATURE COMMUNICATIONS
出版年:2020
卷:11
期:1
DOI:10.1038/s41467-019-14133-x
摘要:Predator-prey interactions play important roles in the cycling of marine organic matter. Here we show that a Gram-negative bacterium isolated from marine sediments (Pseudoalteromonas sp. strain CF6-2) can kill Gram-positive bacteria of diverse peptidoglycan (PG) chemotypes by secreting the metalloprotease pseudoalterin. Secretion of the enzyme requires a Type II secretion system. Pseudoalterin binds to the glycan strands of Gram positive bacterial PG and degrades the PG peptide chains, leading to cell death. The released nutrients, including PG-derived D-amino acids, can then be utilized by strain CF6-2 for growth. Pseudoalterin synthesis is induced by PG degradation products such as glycine and glycine-rich oligopeptides. Genes encoding putative pseudoalterin-like proteins are found in many other marine bacteria. This study reveals a new microbial interaction in the ocean.
收录类别:SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077940908&doi=10.1038%2fs41467-019-14133-x&partnerID=40&md5=bfe17fb11fe02bc876dc151860536b17
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