标题:Construction of N-Heterocycles through Cyclization of Tertiary Amines
作者:Liu, Shuya; Zhao, Zhiguo; Wang, Yao
作者机构:[Liu, Shuya; Zhao, Zhiguo; Wang, Yao] Shandong Univ, Sch Chem & Chem Engn, Minist Educ, Key Lab Colloid & Interface Chem, 27 Shanda Nanlu, Jinan 25010 更多
通讯作者:Wang, Yao;Wang, Y
通讯作者地址:[Wang, Y]Shandong Univ, Sch Chem & Chem Engn, Minist Educ, Key Lab Colloid & Interface Chem, 27 Shanda Nanlu, Jinan 250100, Shandong, Peoples R China.
来源:CHEMISTRY-A EUROPEAN JOURNAL
出版年:2019
卷:25
期:10
页码:2423-2441
DOI:10.1002/chem.201803960
关键词:catalysis; cyclization; cycloaddition; N-heterocycles; tertiary amines
摘要:N-Heterocycles have been found in a large number of natural products, drug molecules, and bioactive compounds, and they thereby play a vital role in diverse research disciplines including drug discovery, organic synthesis, chemical biology, and material science. To this end, the development of new methods and strategies for the construction of N-heterocyclic frameworks is arguably one of the most dynamic and significant research areas in organic synthesis. One of these powerful approaches to the synthesis of N-heterocycles is to establish cyclization reactions based on the transformation of tertiary amines, which has emerged as an attractive research topic. In this Minireview, the significant achievements in the construction of N-heterocycles through cyclization of tertiary amines are highlighted and a comprehensive overview of the rational design, development, and application of these synthetic methods is presented.
收录类别:EI;SCOPUS;SCIE
Scopus被引频次:1
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058716779&doi=10.1002%2fchem.201803960&partnerID=40&md5=79321f8ffa1765ae4b9686349014c01a
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