标题：Polyaniline-based glucose biosensor: A review
作者：Lai, Jiahui; Yi, Yingchun; Zhu, Ping; Shen, Jing; Wu, Kesen; Zhang, Lili; Liu, Jian
作者机构：[Lai, Jiahui; Zhu, Ping; Wu, Kesen; Liu, Jian] Shandong Univ, Sch Control Sci & Engn, Dept Biomed Engn, Jinan 250061, Peoples R China.; [Yi, Yingchu 更多
通讯作者地址：[Liu, J]Shandong Univ, Sch Control Sci & Engn, Dept Biomed Engn, Jinan 250061, Peoples R China;[Zhang, LL]Qilu Univ Technol, Sch Mech & Automot Engn, 更多
来源：JOURNAL OF ELECTROANALYTICAL CHEMISTRY
关键词：Polyaniline; Electron mediator; Glucose; Biosensor; Enzyme electrodes
摘要：The aim of this review is to provide a detailed report of the glucose biosensor based on polyaniline. This conducting polymer not only has been widely used as matrix for immobilization of glucose oxidase, but also can act as electron mediator during enzymatic reaction process due to its outstanding features such as high conductivity, exceptional environmental stability in air, tunable electrochemical properties, biocompatibility, and more. In the paper, the early development history of conventional polyaniline for glucose biosensors is reviewed. And then the shift from conventional polyaniline matrix to composite matrices is discussed by focusing on improving the selectivity and stability of the glucose biosensor. Finally, because of their enhanced electrochemical reactivity, the nanostructured polyaniline and its conjugation with other nanomaterials are reviewed for developing high-performance glucose biosensors. Overall, the evolution of polyaniline is described in detail from conventional matrix to polyaniline composites and then to the nanostructured polyaniline for exploring a sensitive, stable and reliable glucose biosensor. (C) 2016 Elsevier B.V. All rights reserved.