标题：Neurological Manifestations of Dengue Infection
作者：Li, Guo-Hong; Ning, Zhi-Jie; Liu, Yi-Ming; Li, Xiao-Hong
作者机构：[Li, Guo-Hong; Li, Xiao-Hong] Shandong Univ, Jinan Cent Hosp, Dept Neurol, Jinan, Shandong, Peoples R China.; [Ning, Zhi-Jie] Jinan Infect Dis Hosp, 更多
通讯作者：Li, XH;Liu, YM
通讯作者地址：[Li, XH]Shandong Univ, Jinan Cent Hosp, Dept Neurol, Jinan, Shandong, Peoples R China;[Liu, YM]Shandong Univ, Dept Neurol, Qilu Hosp, Jinan, Shandong, 更多
来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
关键词：dengue; neurological complications; neuropathogenesis; in children;; manifestations; treatment; prevention
摘要：Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year > 2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis. In addition, neurological complications in children were assessed due to their atypical clinical features. Finally, dengue infection and Japanese encephalitis were compared for pathogenesis and main clinical manifestations.