标题：Recent development of boronic acid-based fluorescent sensors
作者：Fang, Guiqian; Wang, Hao; Bian, Zhancun; Sun, Jie; Liu, Aiqin; Fang, Hao; Liu, Bo; Yao, Qingqiang; Wu, Zhongyu
作者机构：[Fang, Guiqian; Wang, Hao; Bian, Zhancun; Sun, Jie; Liu, Aiqin; Liu, Bo; Yao, Qingqiang; Wu, Zhongyu] Univ Jinan Shandong Acad Med Sci, Sch Med & Life 更多
通讯作者：Wu, ZY;Wu, ZY;Wu, ZY;Wu, ZY;Wu, Zhongyu
通讯作者地址：[Wu, ZY]Univ Jinan Shandong Acad Med Sci, Sch Med & Life Sci, Jinan 250200, Shandong, Peoples R China;[Wu, ZY]Shandong Acad Med Sci, Inst Mat Med, Jin 更多
摘要：As Lewis acids, boronic acids can bind with 1,2- or 1,3-diols in aqueous solution reversibly and covalently to form five or six cyclic esters, thus resulting in significant fluorescence changes. Based on this phenomenon, boronic acid compounds have been well developed as sensors to recognize carbohydrates or other substances. Several reviews in this area have been reported before, however, novel boronic acid-based fluorescent sensors have emerged in large numbers in recent years. This paper reviews new boron-based sensors from the last five years that can detect carbohydrates such as glucose, ribose and sialyl Lewis A/X, and other substances including catecholamines, reactive oxygen species, and ionic compounds. And emerging electrochemically related fluorescent sensors and functionalized boronic acid as new materials including nanoparticles, smart polymer gels, and quantum dots were also involved. By summarizing and discussing these newly developed sensors, we expect new inspiration in the design of boronic acid-based fluorescent sensors.