标题：Malignant Female Adnexal Tumor of Probable Wolffian Origin: Case Report and Literature Review
作者：Hong, Shuhui; Cui, Jing; Li, Li; Buscema, Joseph; Liggins, Casandra; Zheng, Wenxin
作者机构：[Hong, Shuhui] Shandong Univ, Dept Gynecol, Shandong Prov Qianfoshan Hosp, Jinan, Shandong, Peoples R China.; [Cui, Jing] Shandong Univ, Dept Pathol 更多
通讯作者地址：[Zheng, WX]Univ Texas Southwestern Med Ctr Dallas, Dept Pathol Obstet & Gynecol, 6000 Harry Hines Blvd,NB6-408, Dallas, TX 75390 USA.
来源：INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
关键词：Female adnexal tumor; Wolffian tumor; Ovarian cancer
摘要：Although most female adnexal tumors of probable Wolffian origin have a benign biologic behavior, occasional cases have exhibited malignant potential. We encountered a 50-yr-old woman with an uncommon female adnexal tumors of probable Wolffian origin, which involved bilateral ovaries, invaded the ipsilateral fallopian tube, and extended to the uterine serosa. The initial histopathologic presentation caused significant confusion in pathologic diagnosis. Multiple differential diagnoses including ovarian endometrioid carcinoma, Sertoli cell tumor, and metastasis from nongynecologic organs were considered. After careful examination of the histologic findings and a thorough investigation with multiple immunohistochemical stains, the diagnosis was ultimately established. A literature review on female adnexal tumors of probable Wolffian origin including a malignant form is presented.