标题：Endometrial precancers: From concept to practice
作者机构：[Abushahin, N] Department of Pathology, Faculty of Medicine, The University of Jordan, Amman, Jordan;[ Zhao, R] Department of Obstetrics and Gynecolog 更多
通讯作者地址：[Abushahin, N] Department of Pathology, Faculty of Medicine, The University of Jordan, Amman, Jordan
关键词：Endometrial cancer;Endometrial glandular dysplasia;Endometrial hyperplasia;Endometrial intraepithelial carcinoma;Endometrial intraepithelial neoplasia;Precancer
摘要：Endometrial epithelial cancers are among the most common gynaecological malignancies, with significant numbers of new cases and cancer deaths each year. Recent major advancements in defining the clinicopathologic, molecular and epidemiologic profiles of these cancers has established the existence of two major types of endometrial carcinomas, namely type I and type II endometrial carcinomas. Naturally, distinct precancerous lesions have also been proposed for these two types of endometrial cancer. This review summarizes the distinct histotypes of endometrial cancers, and discusses their corresponding precancers in detail, including the most relevant recent advances and clinical management.