标题:Flow-injection-chemiluminescence method for the determination of penicillin G potassium
作者:Cao, W; Yang, JH; Sun, CX; Zhang, ZJ; Gao, QF
通讯作者:Yang, JH
作者机构:[Cao, W; Yang, JH; Sun, CX; Zhang, ZJ; Gao, QF]Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China.;[Cao, W; Yang, 更多
会议名称:11th International Symposium on Luminescence Spectrometry - Detection Techniques in Biomedical and Environmental Analysis
会议日期:MAY 05-08, 2004
来源:LUMINESCENCE
出版年:2005
卷:20
期:4-5
页码:238-242
DOI:10.1002/bio.839
关键词:penicillin G potassium; chemiluminescence; flow-injection; potassium; permanganate; formaldehyde
摘要:The degradation product of penicillin G potassium can react with potassium permanganate in acidic medium and produce chemiluminescence, which is greatly enhanced by formaldehyde. The optimum conditions for this chemiluminescent reaction were studied in detail using a flow-injection system. The experiments indicated that under optimum conditions, the chemiluminescence intensity was linearly related to the concentration of penicillin G potassium within the range 1.0 x 10(-7)-1.0 x 10(-5) g/mL, with a detection limit (3 sigma) of 7 x 10(-8) g/mL. The relative standard deviation was 1.0% for 4.0 x 10(-7) g/mL penicillin G potassium solution (n = 11). This method has the advantages of simple operation, fast response and high sensitivity. The method was successfully applied to the analysis of penicillin G potassium in raw medicines. Copyright (c) 2005 John Wiley & Sons, Ltd.
收录类别:CPCI-S;SCOPUS;SCIE
WOS核心被引频次:6
Scopus被引频次:8
资源类型:会议论文;期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-25444501794&doi=10.1002%2fbio.839&partnerID=40&md5=0e0c48240fa0f900442977a081e44416
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