标题：Effect of methyl and hydroxyl functional group surfaces on crystallization of hydroxyapatite coating
作者：Wu, Dong-Jin; Liu, Zhi-Xu; Gao, Chun-Zheng; Shen, Xing-Can; Wang, Xiu-Mei; Liang, Hong
作者机构：[Wu, Dong-Jin; Gao, Chun-Zheng; Wang, Xiu-Mei] Shandong Univ, Hosp 2, Dept Orthoped, Jinan 250033, Peoples R China.; [Liu, Zhi-Xu; Wang, Xiu-Mei] Ts 更多
会议名称：8th Asian-European International Conference on Plasma Surface Engineering (AEPSE)
会议日期：SEP 19-22, 2011
来源：SURFACE & COATINGS TECHNOLOGY
关键词：Biomineralization; Self-assembled monolayer; Hydroxyapatite;; Crystallization
摘要：The effect of chemical functional groups and condition of supersaturated solutions are two important factors to induce the nucleation of hydroxyapatite onto the substrates. Two kinds of self-assembled monolayers were prepared to create functionalized surfaces by grafting thioalcohol molecular containing hydroxyl and methyl as terminal groups respectively onto single silicon chips. Atomic force microscopy and X-ray photoelectron spectroscopy were used to analyze the topography of the surfaces and estimate the surface density. The results provided the evidences that our experiments were made with almost the same density of chemical functional groups. The surfaces were incubated in the supersaturated solutions (37 degrees C, pH = 7.4) whose Ca2+ and PO43- concentrations were 1.5 times higher than in simulated body fluid. With the condition mentioned above, this study demonstrates that the growth process and morphology of HAp crystals present great differences. (C) 2012 Published by Elsevier B.V.