标题：Intravenous injection of human umbilical cordderived mesenchymal stem cells for the treatment of sudden sensorineural hearing loss: A case report
作者：Liu, Hua ;Qu, Zhiping ;Sun, Shanhui ;Xiao, Dongjie ;Yang, Tan ;Chen, L. ;Wang, Yunshan
作者机构：[Liu, Hua ;Sun, Shanhui ;Xiao, Dongjie ;Yang, Tan ;Wang, Yunshan ] Central Laboratory, Jinan Central Hospital Affiliated to Shandong University, China 更多
会议名称：2014 International Conference on Medical Engineering and Bioinformatics, MEB 2014
会议日期：7 April 2014 through 8 April 2014
来源：WIT Transactions on Biomedicine and Health
关键词：Intravenous injection; Mesenchymal stem cells; Sensorineural hearing loss
摘要：This study was performed to examine the effect of transplantation of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) on hearing restoration in a sensorineural hearing loss patient. Human umbilical cord was collected from infant after obtaining the family members consent, and UC-MSCs were extracted. A case of sudden sensorineural hearing loss without other neurological deficits in a 48-year-old male showed no therapeutic response after treatment with medicine for one month. An alternative approach with UC-MSCs was applied to this patient by intravenous injection. After second injection of UCMSCs, the patient presented significant improvement in hearing compared to that one month ago. This case indicates that intravenous injection of UC-MSCs can be used in the treatment of sudden sensorineural hearing loss. © 2014 WIT Press.