标题:Peniciketals A-C, New Spiroketals from Saline Soil Derived Penicillium raistrichii
作者:Wei-Zhong Liu;Li-Ying Ma;De-Sheng Liu;Yu-Ling Huang;Chun-Hua Wang;Shou-Sen Shi;Xiao-Hong Pan;Xiao-Dong Song;Rong-Xiu Zhu
作者机构:[Liu, W.-Z] Pharmacy of College, Binzhou Medical College, Yantai 264003, China;[ Ma, L.-Y] Pharmacy of College, Binzhou Medical College, Yantai 264003 更多
通讯作者:Wang, CH
通讯作者地址:[Wang, CH]Binzhou Med Coll, Coll Pharm, Yantai 264003, Peoples R China.
来源:Organic letters
出版年:2014
卷:16
期:1
页码:90-93
DOI:10.1021/ol403076s
关键词:configurations;Penicillium;benzo-fused
摘要:Peniciketals A-C (1-3), three new spiroketals with a benzo-fused 2,8-dioxabicyclo[3.3.1]nonane moiety, were isolated from the saline soil derived fungus Penicillium raistrichii. Their structures including absolute configurations were established by NMR, X-ray diffraction, and ECD calculations. Their cytotoxicities were tested against A549, HL-60, and K562 cell lines, and 1-3 showed the selective effects on HL-60 cells with IC_(50) values of 3.2, 6.7, and 4.5 μM, respectively.
收录类别:SCOPUS;SCIE
WOS核心被引频次:9
Scopus被引频次:13
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891814252&doi=10.1021%2fol403076s&partnerID=40&md5=fefed32c8c962f24bb537b3b32c9f6f4
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