标题:Effect of Fiberoptic Collimation Technique on 808 nm Wavelength Laser Stimulation of Cochlear Neurons
作者:Wang, Jingxuan; Lu, Jianren; Tian, Lan
作者机构:[Wang, Jingxuan; Lu, Jianren; Tian, Lan] Shandong Univ, Sch Informat Sci & Engn, Jinan 250100, Shandong, Peoples R China.
通讯作者:Tian, Lan
通讯作者地址:[Tian, L]Shandong Univ, Sch Informat Sci & Engn, Jinan 250100, Shandong, Peoples R China.
来源:PHOTOMEDICINE AND LASER SURGERY
出版年:2016
卷:34
期:6
页码:252-257
DOI:10.1089/pho.2015.4065
摘要:Objective: The purpose of this study was to evaluate the effects of fiberoptic collimation technique on auditory neural stimulation in the cochlea with 808 nm wavelength lasers. Background data: Recently, the pulsed near-infrared lasers in the 800-1000 nm wavelength range have been investigated as an emerging technique to trigger auditory neural response in the cochlea. A laser beam divergence in the optical stimulation pathway exists, which may affect stimulation efficiency and spatial selectivity. Methods: The fiberoptic collimation technique was proposed for cochlear neuron stimulation, and the C-lens element was designed as the collimation structure. The spiral ganglion cells in deafened guinea pigs' cochlea were irradiated with collimated and uncollimated near-infrared lasers. Optically evoked auditory brainstem response (OABR) under the two laser output modes were recorded. Results: Laser with the collimation technique evoked an average 58% higher OABR amplitude than the uncollimated laser output. In addition, the collimated laser setup consumed on average 35.2% of laser energy compared with the uncollimated laser when evoking the same OABR amplitude. Conclusions: The fiberoptic collimation technique improved stimulation efficiency and reduced stimulating energy consumption in near-infrared neural stimulation in cochlea. The positive effects of laser collimation technique could benefit further research in optically based cochlear implants.
收录类别:EI;SCOPUS;SCIE
WOS核心被引频次:2
Scopus被引频次:3
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973335111&doi=10.1089%2fpho.2015.4065&partnerID=40&md5=f3681a08a65a60824128f1b2e84e0b71
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