标题:Novel self-healing dental resin with microcapsules of polymerizable triethylene glycol dimethacrylate and N,N-dihydroxyethyl-p-toluidine
作者:Wu, Junling; Weir, Michael D.; Zhang, Qiang; Zhou, Chuanjian; Melo, Mary Anne S.; Xu, Hockin H. K.
作者机构:[Wu, Junling] Shandong Univ, Sch Stomatol, Dept Prosthodont, Shandong Prov Key Lab Oral Biomed, Jinan 250012, Peoples R China.; [Wu, Junling; Weir, 更多
通讯作者:Xu, Hockin HK
通讯作者地址:[Xu, HHK]Univ Maryland, Sch Dent, Biomat & Tissue Engn Div, Dept Endodont Prosthodont & Operat Dent, Baltimore, MD 21201 USA.
来源:DENTAL MATERIALS
出版年:2016
卷:32
期:2
页码:294-304
DOI:10.1016/j.dental.2015.11.014
关键词:Self-healing dental resin; Microcapsules; Polymerizable healing liquid;; Mechanical properties; Fracture toughness recovery; Cytotoxicity
摘要:Objective. Bulk fracture is one of the primary reasons for resin-based dental restoration failures. To date, there has been no report on the use of polymerizable dental monomers with acceptable biocompatibility to develop a resin with substantial self-healing capability. The objectives of this study were to: (1) develop a self-healing resin containing microcapsules with triethylene glycol dimethacrylate (TEGDMA)-N,N-dihydroxyethyl-p-toluidine (DHEPT) healing liquid in poly(urea-formaldehyde) (PUF) shells for the first time, and (2) determine the physical and mechanical properties, self-healing efficiency, and fibroblast cytotoxicity.; Methods. Microcapsules of polymerizable TEGDMA-DHEPT in PUF were prepared via an in situ polymerization method. Microcapsules were added into a BisGMA-TEGDMA resin at micro capsule mass fractions of 0%, 5%, 10%, 15% and 20%. A flexural test was used to measure composite strength and elastic modulus. A single edge V-notched beam method was used to measure fracture toughness K-IC and self-healing efficiency.; Results. Flexural strength and elastic modulus (mean +/- sd; n = 6) of resin containing 5-15% microcapsules were similar to control without microcapsules (p > 0.1). Adding microcapsules into the resin increased the virgin K-IC, which was about 40% higher at 15% microcapsules than that with 0% microcapsules (p < 0.05). Specimens were fractured and healed, then fractured again to measure the healed K-IC. A self-healing efficiency of about 65% in K-IC recovery was obtained with 10-20% microcapsules. All specimens with 0-20% microcapsules had fibroblast viability similar to control without resin eluents (p > 0.1).; Significance. Self-healing dental resin containing microcapsules with polymerizable TEGDMA-DHEPT healing liquid in PUF shells were prepared for the first time with excellent self-healing capability. These microcapsules and self-healing resins containing them may be promising for dental restorations to heal cracks/damage and increase durability. (C) 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
收录类别:EI;SCOPUS;SCIE
WOS核心被引频次:7
Scopus被引频次:7
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84957844424&doi=10.1016%2fj.dental.2015.11.014&partnerID=40&md5=f9ed3e3c081f05724329ebf46fe111ef
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