标题：Chinese contribution to immune thrombocytopenia: the pathogenesis-oriented treatment
作者：Qin Ping; Peng Jun; Hou Ming
作者机构：[Qin, P] Department of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China;[ Peng, J] Department of Hematology, Qilu Hospita 更多
通讯作者地址：[Hou, M]Shandong Univ, Dept Hematol, Qilu Hosp, Jinan 250012, Shandong, Peoples R China.
摘要：Primary immune thrombocytopenia (ITP) is the most common hemorrhagic disorder characterized by isolated thrombocytopenia in the absence of conditions known to cause thrombocytopenia.The incidence rate of ITP is similar in males and females;the incidence was significantly higher among patients older than 60 years.1 The clinical manifestation of bleeding varies with patient.The severity of bleeding ranges from mild mucocutanous bleeding (petechiae and ecchymoses) to life-threatening hemorrhages (intracranial or gastrointestinal bleeding);some patients have no bleeding manifestations.Fatal and major nonfatal hemorrhages were extremely higher in patients older than 60 years old.2