标题:One-pot enzyme- and indicator-free colorimetric sensing of glucose based on MnO2 nano-oxidizer
作者:Zhang, Jiling; Dai, Xin; Song, Zhi-Ling; Han, Rui; Ma, Linzheng; Fan, Gao-Chao; Luo, Xiliang
作者机构:[Zhang, Jiling; Dai, Xin; Song, Zhi-Ling; Han, Rui; Fan, Gao-Chao; Luo, Xiliang] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Key Lab Opt Elect S 更多
通讯作者:Song, ZL;Luo, XL
通讯作者地址:[Song, ZL; Luo, XL]Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Key Lab Opt Elect Sensing & Analyt Chem Life Sci, MOE, Qingdao 266042, Shandong, 更多
来源:SENSORS AND ACTUATORS B-CHEMICAL
出版年:2020
卷:304
DOI:10.1016/j.snb.2019.127304
关键词:MnO2; Glucose; Colorimetric detection; Nano-oxidizer; Enzyme-free
摘要:To establish more stable and lower cost colorimetric methods for the sensing of glucose, the artificial nanozymes were developed as the substitutes of natural enzymes (glucose oxidase, GOx; peroxidase). However, the common utilized nanozymes cannot show both the tandem enzymatic activities and the color indicating performance at the same time, which lead to the further addition of natural enzyme or color indicator. To overcome these problems, we fabricate a novel one-pot enzyme- and indicator-free method for the colorimetric sensing of blood glucose levels based on the direct redox reaction of MnO2/glucose. The MnO2 nanomaterial is acted as an active nano-oxidizer, and a color nano-indicator for the sensing of blood glucose levels. In the presence of target glucose, the MnO2 nano-oxidizers is reduced to Mn2+, leading to the dramatic decreasing absorbance and fading color of yellow MnO2 solution. This nanosystem demonstrates wide liner range from 10 mu M to 5mM with low detectable limit of 10 mu M. In addition, it shows favorable applicability for the glucose monitoring in human blood sample. Our proposed strategy takes advantage of the direct redox reaction of glucose and MnO2, which eliminates the use of natural enzymes (GOx, peroxidase) and the color indicator, and realized a sensitive, low-cost and convenient method for the colorimetric sensing of glucose.
收录类别:SCOPUS;SCIE
WOS核心被引频次:1
Scopus被引频次:2
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074158130&doi=10.1016%2fj.snb.2019.127304&partnerID=40&md5=583cf67b7f8a9c524e3a5b392dc92b17
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