标题：Synthesis of a tetrasaccharide repeating unit of the exopolysaccharide from Burkholderia multivorans
作者：Zhang, Xin; Wang, Dongyue; Jin, Guoxia; Wang, Lizhen; Guo, Zhongwu; Gu, Guofeng
作者机构：[Zhang, Xin; Wang, Dongyue; Wang, Lizhen; Guo, Zhongwu; Gu, Guofeng] Shandong Univ, Shandong Prov Key Lab Carbohydrate Chem & Glycobi, Natl Glycoengn 更多
通讯作者地址：[Gu, GF]Shandong Univ, Shandong Prov Key Lab Carbohydrate Chem & Glycobi, Natl Glycoengn Res Ctr, 27 Shanda Nan Lu, Jinan 250100, Shandong, Peoples R 更多
来源：JOURNAL OF CARBOHYDRATE CHEMISTRY
关键词：Burkholderia multivorans; Exopolysaccharide; Synthesis; Glycosylation
摘要：The chemical synthesis of a tetrasaccharide repeating unit of the exopolysaccharide discovered from Burkholderia multivorans with a 3-aminopropyl group linked to the glycan downstream end, -D-Manp-(12)--D-Manp-(12)-3-O-methyl--D-Rhap-(13)--D-Rhap-O(CH2)(3)NH2 (1), was described. The target tetrasaccharide was achieved by both a convergent [2 + 2] and a linear glycosylation strategies. The latter synthesis was proved to be more efficient than the former due to the excellent stereocontrol of glycosylation. Furthermore, the 3-aminopropyl group in the target molecule would enable its conjugation with functional biomolecules to explore its biological applications.