标题:Coumarin-based fluorescent probes for H_2S detection
作者:Li, W.;Sun, W.;Yu, X.;Du, L.;Li, M.
作者机构:[Li, W] Department of Medicinal Chemistry, School of Pharmacy, Shandong University, Jinan Shandong 250012, China;[ Sun, W] Department of Medicinal Che 更多
通讯作者:Li, M
通讯作者地址:[Li, MY]Shandong Univ, Sch Pharm, Key Lab Chem Biol Nat Prod MOE, Dept Med Chem, Jinan 250012, Shandong, Peoples R China.
来源:Journal of Fluorescence
出版年:2013
卷:23
期:1
页码:181-186
DOI:10.1007/s10895-012-1131-4
关键词:Cell imaging;Coumarin;Fluorescent probe;H_2S
摘要:Although hydrogen sulfide (H_2S) has been known as a toxic gas with unpleasant rotten egg smell, the correlation between H_2S and physiological processes has attracted scientists to develop brand new methods to monitor such a gaseous molecule in vitro and in vivo. Herein, we described a couple of coumarin-based fluorescent probes (1a and 1b) that can be activated by reduction of azide to amine in the presence of H_2S. It should be emphasized that probe 1b demonstrated high selectivity and sensitivity for H_2S over other relevant reactive sulfur species in vitro, as well as identified exogenous H_2S in living cells.
收录类别:EI;SCOPUS;SCIE
WOS核心被引频次:34
Scopus被引频次:37
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873157162&doi=10.1007%2fs10895-012-1131-4&partnerID=40&md5=da3347673c54966f3d8740f2638b5ebe
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