标题:The value of 18F-FDG PET/CT in patient with neurofibromatosis type 1: A case report and literature review
作者:Ren, Jiazhong; Yang, Guoren; Zhou, Jing; Fu, Zheng
作者机构:[Ren, Jiazhong] Jining 1 Peoples Hosp, Dept Radiol, Jining, Shandong, Peoples R China.; [Yang, Guoren] Shandong Univ, Shandong Canc Hosp, Dept Nucl 更多
通讯作者:Fu, Z
通讯作者地址:[Fu, Z]Shandong Univ, Shandong Canc Hosp, Dept Imaging, Shandong Acad Med Sci, Jinan 250117, Shandong, Peoples R China.
来源:MEDICINE
出版年:2018
卷:97
期:20
DOI:10.1097/MD.0000000000010648
关键词:F-18-FDG PET; CT; cafe-au-lait macules; neurofibromatosis
摘要:Rationale:Neurofibromatosis type one (NF1) is characterized by cutaneous and nervous lesions, and the tendency to form plexiform neurofibromas (PNFs). PNFs may undergo malignant transformation into a malignant peripheral nerve sheath tumors (MPNSTs). MPNSTs often carry an significant morbidity and mortality.Patient concerns:A 17-year-old man with gradually increased multiple subcutaneous soft lesions. He also presented with numerous lentigines and multiple cafe-au-lait macules on his body.Diagnoses:These were collagen neurofibroma, which were definitively diagnosed by pathology. NF1 was eventually diagnosed.Interventions:These lesions were abnormal uptake of radiotracer, when he underwent positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) scanning. Standard uptake value (SUV) and other parameters can help to distinguish benign and malignant lesions in patient with NF1. He was underwent serials F-18-FDG PET/CT examinations to followed up, in order to monitor these lesions malignant transformation.Outcomes:So far, these subcutaneous soft lesions were not malignant transformation.Lessons:F-18-FDG PET/CT is being increasingly used as an imaging modality to discover the systemic lesions and to discriminate between benign and malignant plexiform neurofibromas.
收录类别:SCIE
资源类型:期刊论文
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