标题:Exploration of the Radiotherapeutic Clinical Target Volume Delineation for Gastric Cancer from Lymph Node Metastases
作者:Dong, Wei; Li, Baosheng; Wang, Juan; Song, Yipeng; Zhang, Zicheng; Fu, Chengrui
通讯作者:Song, YP;Li, BS
作者机构:[Dong, Wei] Shandong Univ, Sch Med, Jinan, Shandong, Peoples R China.; [Dong, Wei; Song, Yipeng] Qingdao Univ, Affiliated Yantai Yuhuangding Hosp, R 更多
会议名称:China-United Kingdom Cancer (CUKC) Conference
会议日期:APR 22-23, 2017
来源:ANTICANCER RESEARCH
出版年:2017
卷:37
期:8
页码:4629-4634
DOI:10.21873/anticanres.11864
关键词:Gastric cancer; radiotherapy; regional lymph nodes; delineation
摘要:Aim: To clarify the clinical target volume of regional lymph nodes (CTVn) delineation of gastric adenocarcinoma. Materials and Methods: The pattern of lymph node metastases (LNM) of a total of 1,473 patients with gastric cancer (GC) who had undergone gastrectomy and lymphadenectomy with more than 15 lymph nodes retrieved was retrospectively examined. Results: A univariate analysis showed that T stage (p<0.001), macroscopic type (p=0.001), tumor differentiation (p<0.001), maximum diameter of tumor (p<0.001) as well as cancer embolus (p<0.001) were closely associated with the rate of LNM. While by multivariate analysis, gender [odds ratio (OR=0.687, p<0.05], maximum diameter (OR=1.734, p<0.001), tumor differentiation (OR=1.584, p<0.001), T stage (OR=2.066, p<0.001) and cancer embolus (OR=4.912, p<0.001) were strongly associated with the rate of LNM. Conclusion: In conclusion, for male patients with GC with large, deeply invasive, poorly differentiated, diffusely infiltration and positive cancer embolus, the radiation fields should be enlarged appropriately.
收录类别:CPCI-S;SCOPUS;SCIE
资源类型:会议论文;期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026258179&doi=10.21873%2fanticanres.11864&partnerID=40&md5=78c8f07e1273e0c73d905d1a9bba6fad
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