标题:A triple-amplification strategy for sensitive detection of telomerase at the single-cell level
作者:Li C.-C.; Zhang Y.; Liu W.-J.; Zhang C.-Y.
作者机构:[Li, C.-C] College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Ima 更多
通讯作者:Zhang, CY(cyzhang@sdnu.edu.cn)
通讯作者地址:[Zhang, C.-Y] College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical 更多
来源:Chemical Communications
出版年:2018
卷:54
期:67
页码:9317-9320
DOI:10.1039/c8cc05100c
摘要:We develop a triple-amplification strategy for sensitive detection of telomerase from cancer cells using telomere-based primer generation-triggered rolling circle amplification in combination with enzyme-assisted cyclic signal amplification. This method can detect telomerase at the single-cell level, and it can be further applied for the screening of telomerase inhibitors for anticancer drug discovery. © The Royal Society of Chemistry.
收录类别:SCOPUS
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052068217&doi=10.1039%2fc8cc05100c&partnerID=40&md5=39e81fedc75e0e2bf49dff71c6e05194
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