标题:Thyroid-like Follicular Carcinoma of the Kidney and Papillary Renal Cell Carcinoma with Thyroid-like Feature: Comparison of Two Cases and Literature Review
作者:Li, Congcong; Dong, Hongyan; Fu, Weiwei; Qi, Mei; Han, Bo
作者机构:[Li, Congcong; Dong, Hongyan; Fu, Weiwei; Qi, Mei; Han, Bo] Shandong Univ, Dept Pathol, Qilu Hosp, Jinan 250012, Peoples R China.; [Dong, Hongyan] L 更多
通讯作者:Han, B
通讯作者地址:[Han, B]Shandong Univ, Dept Pathol, Qilu Hosp, 107 Wenhua Xi Rd, Jinan 250012, Peoples R China.
来源:ANNALS OF CLINICAL AND LABORATORY SCIENCE
出版年:2015
卷:45
期:6
页码:707-712
关键词:Thyroid-like follicular carcinoma of the kidney; papillary renal cell; carcinoma; differential diagnosis
摘要:Thyroid-like follicular carcinoma of the kidney (TLFCK) is a provisional new entity of renal cell carcinoma (RCC). We herein reported and compared one TLFCK case and one PRCC case with thyroid-like feature. The former entirely consisted of thyroid-like follicular architecture and the tumor cells were diffusely positive for PAX-8, but negative for CK7, AMACR, and CD10. By contrast, both papillary architecture (similar to 60%) and thyroid-like follicular architecture (similar to 40%) were identified in the latter. Tumor cells in both histological components exhibited diffusely positive staining for PAX-8, CK7, AMACR, but negative for CD10. FISH analysis showed no aberration in TLFCK case but trisomy of chromosome 17 in PRCC case. Along with a brief literature review, we presented that recognition of TLFCK is important to distinguish it from other conditions that show thyroid-like features. Additionally, a diagnosis of TLFCK should be cautiously made when papillary component is present in the tumor.
收录类别:SCOPUS;SCIE
WOS核心被引频次:3
Scopus被引频次:3
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84950252439&partnerID=40&md5=61e5942fe76eddc8b46013fbd0ecc07c
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