标题:Vesicular particles directly assembled from the cyclodextrin/UR-144 supramolecular amphiphiles
作者:Sun, Tao; Ma, Mingfang; Yan, Hui; Shen, Jian; Su, Jie; Hao, Aiyou
作者机构:[Sun, Tao; Ma, Mingfang; Su, Jie; Hao, Aiyou] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.; [Sun, Tao; Ma, Mingfang; Su, Jie; 更多
通讯作者:Hao, Aiyou
通讯作者地址:[Hao, AY]Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.
来源:COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
出版年:2013
卷:424
页码:105-112
DOI:10.1016/j.colsurfa.2013.02.016
关键词:UR-144; Cyclodextrin; Vesicular particle; Supramolecular chemistry;; Controlled release
摘要:Vesicles constructed by supramolecular amphiphiles are considered as more promising stimuli-responsive vehicles for carrying and delivering targeted molecules. In this research, novel supramolecular amphiphiles are directly assembled from UR-144, a general neuropathic drug, and a class of mono-diaminoalkane substituted beta-cyclodextrins. In the aqueous solution, the supramolecular amphiphiles can assemble into vesicular particles, which were characterized in detail by transmission electron microscopy (TEM), atomic force microscopy (AFM), scanning electron microscopy (SEM) and dynamic light scattering (DLS). The mechanism was also suggested based on the NMR, Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) experimental results. The vesicular particles tend to be damaged upon the addition of Cu2+ and meanwhile release UR-144. (C) 2013 Elsevier B.V. All rights reserved.
收录类别:EI;SCOPUS;SCIE
WOS核心被引频次:11
Scopus被引频次:11
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84874766735&doi=10.1016%2fj.colsurfa.2013.02.016&partnerID=40&md5=8f32b2c02486a999632e804d71c5fc39
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