标题：Renal amyloidosis and hepatitis B virus-associated glomerulonephritis in a patient with nephrotic syndrome
作者：Jiang Wei; Xu Yan; Guan Guangju; Ma Ruixia; Dong Hui
作者机构：[Jiang, W] Shandong University, Jinan, Shandong 250014, China, Department of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, Shand 更多
通讯作者地址：[Dong, H]Qingdao Univ, Dept Nephrol, Affiliated Hosp, Qingdao 266003, Shandong, Peoples R China.
摘要：To the editor:A 53-year-old woman presenting with eyelid edema,and foamy urine for a period of 3 years was admitted to the Qingdao Medical College Hospital.She had been a hepatitis B virus (HBV) carrier for 30 years.Upon admission,the 24-hour urinary protein quantity was 3.6 g.Plasma albumin level was 29 g/L.Serum amyloid A (SAA) level was 45 μg/ml.The renal biopsy results are given in Figure 1.Consequently,this case was diagnosed as secondary AA amyloidosis associated with HBV-associated glomerulonephritis (HBV-GN).We believed that HBV infection had a key role in amyloid deposition and heavy proteinuria.Lamivudine was administered orally at 100 mg/d.Six months later,the patient 24-hour urinary protein excretion was 1.0 g,and peripheral edema disappeared completely.