标题：Electrochemiluminescent Immune-Modified Electrodes Based on Ag2Se@CdSe Nanoneedles Loaded with Polypyrrole Intercalated Graphene for Detection of CA72-4
作者：Lv, Xiaohui;Pang, Xuehui;Li, Yueyun;Yan, Tao;Cao, Wei;Du, Bin;Wei, Qin
作者机构：Univ Jinan, Sch Chem & Chem Engn, Key Lab Chem Sensing & Anal Univ Shandong, Jinan 250022, Peoples R China;Univ Jinan, S
通讯作者地址：[Wei, Q]Univ Jinan, Sch Chem & Chem Engn, Key Lab Chem Sensing & Anal Univ Shandong, Jinan 250022, Peoples R China.
来源：ACS applied materials & interfaces
关键词：Ag2Se@CdSe nanoneedles;electrochemiluminescence;modified electrodes;polypyrrole intercalated graphene
摘要：This work described a new electrochemiluminescence (ECL) immunosensor based on polypyrrole intercalated graphene and Ag2Se@CdSe nanoneedles. The novel nanomaterial Ag2Se@CdSe, with needle-like morphology, was synthesized for the first time. The prepared Ag2Se@CdSe nanoneedles exhibited good luminous performance in the presence of K2S2O8. Polypyrrole intercalated amination graphene with high specific binding sites and excellent electrochemical performance was used as the platform for the sensor. The developed ECL immunosensor was used for the detection of CA72-4 with good linear relation in the range from 10(-4) to 20 U/mL and low detection limit of 2.1 x 10(-5) U/mL (S/N = 3). The developed ECL immunosensor with high sensitivity and spectral selectivity can be used for detection of real samples. Ag2Se@CdSe nanoneedles could be promising candidate emitter for ECL biosensors in the future.