标题:Comparison between computed tomography-guided percutaneous microwave ablation and thoracoscopic lobectomy for stage I non-small cell lung cancer
作者:Wang, Yongzheng; Liu, Bin; Cao, Pikun; Wang, Wujie; Wang, Wei; Chang, Haiyang; Li, Dong; Li, Xiao; Zhao, Xiaogang; Li, Yuliang
作者机构:[Wang, Yongzheng; Liu, Bin; Wang, Wujie; Wang, Wei; Chang, Haiyang; Li, Yuliang] Shandong Univ, Hosp 2, Dept Intervent Med, 247 Beiyuan Rd, Jinan 2500 更多
通讯作者:Li, YL
通讯作者地址:[Li, YL]Shandong Univ, Hosp 2, Dept Intervent Med, 247 Beiyuan Rd, Jinan 250033, Shandong, Peoples R China.
来源:THORACIC CANCER
出版年:2018
卷:9
期:11
页码:1376-1382
DOI:10.1111/1759-7714.12842
关键词:Disease free survival; microwave ablation; non-small-cell lung cancer;; overall survival; surgery
摘要:Background Methods The study was conducted to investigate the effectiveness and cost of computed tomography (CT)-guided percutaneous microwave ablation (MWA) and thoracoscopic lobectomy for stage I non-small cell lung cancer (NSCLC). We retrospectively analyzed the data of 46 and 85 patients with stage I NSCLC treated with CT-guided percutaneous MWA or thoracoscopic lobectomy, respectively, at our center from July 2013 to June 2015. Overall survival (OS), disease-free survival (DFS), local control rate, hospital stay, and cost were evaluated. Survival curves were constructed using the Kaplan-Meier method and compared using the log-rank test. Results Conclusion The one and two-year OS rates were 97.82% and 91.30% and 97.65% and 90.59% in the MWA and lobectomy groups, respectively. The one and two-year DFS rates were 95.65% and 76.09% and 95.29% and 75.29%, respectively. No significant differences were observed in log-rank analysis between the groups (P = 0.169). The hospital stays in the MWA and lobectomy groups were 6.62 +/- 2.31 and 9.57 +/- 3.19 days, respectively. The costs of MWA and lobectomy were US$3274.50 +/- US$233.91 and US$4678.87 +/- US$155.96, respectively. The differences were all significant (P = 0.003). MWA and thoracoscopic lobectomy for stage I NSCLC demonstrate similar one and two-year OS and DFS, with no significant differences between the two groups. MWA involved a shorter hospital stay and lower cost, thus should be considered a better option for patients with severe cardiopulmonary comorbidity and patients unwilling to undergo surgery.
收录类别:SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052801366&doi=10.1111%2f1759-7714.12842&partnerID=40&md5=9b2fd29d1b89e1395d1479131187e2a3
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