标题:Transcranial Magnetic Stimulation in Schizophrenia: The Contribution of Neuroimaging
作者:Du,Z.-D.;Wang,R.;Prakash,R.;Chaudhury,S.;Ranchi,India;Dayananda,G.
作者机构:Neurology Department, The 89th Hospital of PLA, Weifang, Shandong, China;Cardiology Department, Qilu Hospital of Shandong Univer
通讯作者:Prakash, R
通讯作者地址:[Prakash, R]MS Ramaiah Med Coll & Inst, Dept Physiol, Bangalore, Karnataka, India.
来源:Current topics in medicinal chemistry
出版年:2012
卷:12
期:21
页码:2452-2457
DOI:10.2174/156802612805289908
关键词:Electro-enchephalogram (eeg);Functional neuro-imaging;Mechanism of action;Repetitive transcranial magnetic stimulation (rtms);Schizophrenia
摘要:At the most basic level, the Transcranial Magnetic Stimulation(TMS) is a neuro-scientific tool that exerts its action by influencing the neo-cortical functions. However, in-spite of so many well-evidenced roles of TMS in neuropsychiatric conditions, its exact mechanism of action remains to be known. More intriguing are its therapeutic effects in Schizophrenia at the Cerebral-level. In this review, we adopt a neuro-imaging approach for this exploration. We review the present literature for the studies in Schizophrenia which have used a combination of rTMS with 1) Electroenchephalogram (EEG) 2)The functional Magnetic Resonance Imaging (fMRI) and the 3) Positron Emission Tomography (PET)/ Single-Photon Emission Computed Tomography. The TMS-EEG combination provides direct effects of TMS on the electro-magnetic field (EMF) of brain. The TMS-fMRI/PET/SPECT combinations are very effective in exploring the functional connectivity in brains of Schizophrenia patients as well as in performing rTMS guided neuro-navigation. Our review suggests that TMS combined with other neuroimaging modalities are needed for a better clarification of its neural actions.
收录类别:SCIE
WOS核心被引频次:3
资源类型:期刊论文
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