标题:Total parathyroidectomy with autotransplantation versus subtotal parathyroidectomy for renal hyperparathyroidism: A systematic review and meta-analysis
作者:Chen, Juan; Jia, Xiaoyan; Kong, Xianglei; Wang, Zunsong; Cui, Meiyu; Xu, Dongmei
作者机构:[Chen, Juan; Jia, Xiaoyan; Kong, Xianglei; Wang, Zunsong; Cui, Meiyu; Xu, Dongmei] Shandong Univ, Dept Nephrol, Affiliated Qianfoshan Hosp, 16766 Jing 更多
通讯作者:Xu, DM
通讯作者地址:[Xu, DM]Shandong Univ, Dept Nephrol, Affiliated Qianfoshan Hosp, 16766 Jingshi Rd, Jinan 250014, Peoples R China.
来源:NEPHROLOGY
出版年:2017
卷:22
期:5
页码:388-396
DOI:10.1111/nep.12801
关键词:Chronic kidney disease; Hyperparathyroidism; Meta-analysis;; Parathyroidectomy
摘要:Aim: Total parathyroidectomy with autotransplantation (TPTX+AT) and subtotal parathyroidectomy (SPTX) have been recommended to patients with renal hyperparathyroidism (RHPT).But which one is the best surgical method remains controversial. The aim of the present study was to compare the two surgical procedures with respect to long-term outcomes.; Methods: A literature search was undertaken using Medline, EMBASE, CNKI and CBM from inception to May 2015. Study quality was assessed using the Newcastle-Ottawa Scale. Data were analyzed using Review Manager version 5.1.0.; Results: A total of 13 studies comprising 1589 patients with renal failure were identified. There was no statistically significant difference in the rate of symptomatic improvement (OR 0.77; 95%CI 0.22 to 2.69; P = 0.68), radiological success (OR 0.17; 95%CI 0.02 to 1.56; P = 0.90), hyperparathyroidism recurrence or persistence (OR 1.31; 95%CI 0.65 to 2.65; P = 0.45) and reoperation (OR 1.55; 95%CI 0.62 to 3.86; P = 0.35) between TPTX+AT and SPTX. The effects on serum calcium and parathyroid hormone (PTH) were similar between two surgical protocols.; Conclusion: Both the TPTX+AT and SPTX were effective in treating RHPT and preventing recurrence. The difference between the two surgeries in recurrence or persistence and reoperation rate was insignificant. Further prospective, randomized controlled trials with high statistic power are necessary to comparative the two surgeries on the long term safety.
收录类别:SCOPUS;SCIE
WOS核心被引频次:3
Scopus被引频次:6
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85016985275&doi=10.1111%2fnep.12801&partnerID=40&md5=97af57cff6bff5207d709e46c2edcd31
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