标题：P21-activated kinase 1 and 4 were associated with colorectal cancer metastasis and infiltration
作者：Song, Bao;Wang, Wei;Zheng, Yan;Yang, Jianshu;Xu, Zhongfa
作者机构：[Song, B] Department of Biochemistry and Molecular Biology, Shandong University, School of Medicine, Jinan, China, Department of Basic Laboratory, Sha 更多
通讯作者地址：[Xu, ZF]Affiliated Hosp Shandong Acad Med Sci, Dept Surg, Jinan 250000, Peoples R China.
来源：Journal of Surgical Research: Clinical and Laboratory Investigation
关键词：P21-activated kinase;Colorectal cancer;Gene expression;Recurrence;Metastasis
摘要：Background: P21-activated kinases (PAKs) are small guanosine triphosphate effectors that play critical roles in many fundamental cellular functions, including cytoskeletal reorganization and cell motility. PAKs are widely expressed in a variety of tissues and are often overexpressed in multiple cancer types. The aim of this study was to investigate the relationship between PAK1 and PAK4 and clinicopathologic features of colorectal cancer.