标题:Effect of transforming growth factor-beta 1 869C/T polymorphism and radiation pneumonitis
作者:Wang, Yingtian; Wang, Xingguang; Wang, Xiyan; Zhang, Deyong; Jiang, Shujuan
作者机构:[Wang, Yingtian; Zhang, Deyong] Dongying Peoples Hosp Shandong Prov, Dept Resp Med, Dongying 257091, Shandong, Peoples R China.; [Wang, Xingguang; J 更多
通讯作者:Wang, YT
通讯作者地址:[Wang, YT]Dongying Peoples Hosp Shandong Prov, Dept Resp Med, Dongying 257091, Shandong, Peoples R China.
来源:INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY
出版年:2015
卷:8
期:3
页码:2835-2839
关键词:Radiation pneumonitis; transforming growth factor; meta-analysis;; polymorphism
摘要:Background: The Transforming growth factor-beta 1 (TGF beta 1) 869C/T polymorphism was associated with radiation pneumonitis (RP) susceptibility. However, the results remained controversial. Thus, a meta-analysis was conducted. Methods: Relevant studies were systematically searched by using the NCBI, Medline, Web of Science and Embase databases. Summary odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated using random-effects models. Results: There was a significant association between TGF beta 1 869C/T polymorphism and RP susceptibility (OR = 1.77; 95% CI, 1.27-2.47; P = 0.0007). Conclusion: This study suggested that TGF beta 1 869C/T polymorphism was a risk factor of RP.
收录类别:SCOPUS;SCIE
WOS核心被引频次:2
Scopus被引频次:3
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84933034171&partnerID=40&md5=04aef8ee5dddcb49f90af1654c0b99e7
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