标题:Alkaloids and Flavonoids as alpha(1)-Adrenergic Receptor Antagonists
作者:Li, W.; Du, L.; Li, M.
作者机构:[Li, W.; Du, L.; Li, M.] Shandong Univ, Dept Med Chem, Sch Pharm, Jinan 250012, Shandong, Peoples R China.
通讯作者:Li, M
通讯作者地址:[Li, M]Shandong Univ, Dept Med Chem, Sch Pharm, Jinan 250012, Shandong, Peoples R China.
来源:CURRENT MEDICINAL CHEMISTRY
出版年:2011
卷:18
期:32
页码:4923-4932
DOI:10.2174/092986711797535209
关键词:alpha(1)-adrenergic receptor; antagonist; natural products; alkaloids;; flavonoids
摘要:Since the subtypes of alpha(1)-adrenergic receptor have been thoroughly determined, to date medicinal chemists raise their deliberation on how to conceive selective alpha(1)-adrenergic receptor antagonist with the minimal side effects. It needs to be well recognized that natural products can exist as a significant source of drug leads, thus portraying a consequential capacity in drug design and development. The current review article would like to present a comprehensive survey on natural products, mainly including alkaloids and flavonoids, which exhibit alpha(1)-adrenergic receptor antagonistic activities.
收录类别:SCOPUS;SCIE
WOS核心被引频次:10
Scopus被引频次:8
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054865004&doi=10.2174%2f092986711797535209&partnerID=40&md5=48dffb153aa84de4931b323b2ea71ecc
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