标题：Advances in the Study of Marine Products with Lipid-Lowering Properties
作者：Zhao, Jiarui; Cao, Qi; Xing, Maochen; Xiao, Han; Cheng, Zeyu; Song, Shuliang; Ji, Aiguo
作者机构：[Zhao, Jiarui; Cao, Qi; Xing, Maochen; Xiao, Han; Cheng, Zeyu; Song, Shuliang; Ji, Aiguo] Shandong Univ, Marine Coll, Weihai 264209, Peoples R China.; 更多
通讯作者地址：Song, SL; Ji, AG (corresponding author), Shandong Univ, Marine Coll, Weihai 264209, Peoples R China.; Ji, AG (corresponding author), Shandong Univ, Sc 更多
关键词：cardiovascular diseases; atherosclerosis; hyperlipidemia; hypolipidemic;; marine products
摘要：With twice the number of cancer's deaths, cardiovascular diseases have become the leading cause of death worldwide. Atherosclerosis, in particular, is a progressive, chronic inflammatory cardiovascular disease caused by persistent damage to blood vessels due to elevated cholesterol levels and hyperlipidemia. This condition is characterized by an increase in serum cholesterol, triglycerides, and low-density lipoprotein, and a decrease in high-density lipoprotein. Although existing therapies with hypolipidemic effects can improve the living standards of patients with cardiovascular diseases, the drugs currently used in clinical practice have certain side effects, which insists on the need for the development of new types of drugs with lipid-lowering effects. Some marine-derived substances have proven hypolipidemic activities with fewer side effects and stand as a good alternative for drug development. Recently, there have been thousands of studies on substances with lipid-lowering properties of marine origin, and some are already implemented in clinical practice. Here, we summarize the active components of marine-derived products having a hypolipidemic effect. These active constituents according to their source are divided into algal, animal, plant and microbial and contribute to the development and utilization of marine medicinal products with hypolipidemic effects.