标题:Carbonylative formation of N-acetyl-2,6-difluorobenzamide through N-H bond activation of 2,6-difluorobenzamide with Ni(II) complex supported with phosphine ligands
作者:Wang, C.;Sun, H.;Hu, Q.;Li, X.
作者机构:School of Chemistry and Chemical Engineering, Shandong University, Shanda Nanlu 27, 250100 Jinan, China;School of Chemistry and
来源:Journal of Organometallic Chemistry
出版年:2011
期:15
页码:2815-2819
关键词:Carbonylation;Imide;Nickel;Organic fluoride;Trimethylphosphine
摘要:Fluorinated imide, N-acetyl-2,6-difluorobenzamide (C_6H _3F_2-2,6)C(O)NHC(O)Me _2, could be obtained through one-pot reaction of NiMe_2(PMe_3)_3 with 2,6-difluorobenzamide (C_6H_3F2-2,6)C(O)NH _2 1 in CO atmosphere. A postulated reaction mechanism via N-H bond cleavage and carbonylative reductive elimination on nickel center was partly experimentally confirmed. An important intermediate (C_6H _3F2-2,6)C(O)HNNiMe(PMe_3)_2 _3 was isolated and structurally characterized.
资源类型:期刊论文
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