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  • 认领成果数 155
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1. The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells SCOPUS PubMed

作者:Wu X.;Li Z.;Shen Y.

作者机构:[Wu, X] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan, Shandong, China;[ Li, Z] Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China;[ Shen, Y] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan, Shandong, China, State Key Laboratory of Microbial Technology, Shandong University, No. 27 South Shanda Road, Jinan, Shandong, China

来源:Biochimica et Biophysica Acta - General Subjects,2018,Vol.1862,Issue.5

最新影响因子:4.702

资源类型:外文期刊论文

2. Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors SCOPUS PubMed

作者:Liang C.;Wu X.;Li Z.;Zhu J.;Lu C.;Shen Y.

作者机构:[Liang, C] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China;[ Wu, X] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China;[ Li, Z] Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China;[ Zhu, J] State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China;[ Lu, C] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China;[ Shen, Y] Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China, State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong, China

来源:European Journal of Medicinal Chemistry,2018,Vol.143

最新影响因子:4.519

资源类型:外文期刊论文

3. Diversity of Polyketide Chains Achieved by Deleting the Tailoring Genes in the Biosynthesis of Ansatrienins SCIE SCOPUS PubMed

作者:Wang, JX;Li, XM;Lu, CH;Shen, YM

作者机构:[Wang, Jianxiong; Li, Xiaoman; Lu, Chunhua; Shen, Yuemao] Shandong Univ, Key Lab Chem Biol, Minist Educ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China.

来源:CHEMBIOCHEM,2018,Vol.19,Issue.3,256-262

最新影响因子:2.847

资源类型:外文期刊论文

WOS被引频次: 0

4. Amexanthomycins A-J, pentangular polyphenols produced by Amycolatopsis mediterranei S699 Delta rifA EI SCIE SCOPUS PubMed

作者:Li, XM;Wu, XK;Zhu, J;Shen, YM

作者机构:[Li, Xiaomei; Wu, Xingkang; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Key Lab Chem Biol, Minist Educ, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Zhu, Jing; Shen, Yuemao] Shandong Univ, State Key Lab Microbial Technol, Jinan 250100, Shandong, Peoples R China.

来源:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,Vol.102,Issue.2,689-702

最新影响因子:3.42

资源类型:外文期刊论文

WOS被引频次: 0

5. Albaflavenone和strepsesquitriol生物合成基因簇在链霉菌SR107菌株中的异源表达揭示二者有共同的生物合成前体epi-isozizaene(英文) 知网

作者:周媛;李善仁;赵贵石;朱敬;鲁春华;沈月毛

作者机构:[周媛;李善仁;赵贵石;朱敬;鲁春华;沈月毛]山东大学药学院天然产物化学生物学教育部重点实验室,山东大学生命科学学院微生物技术国家重点实验室

来源:中国抗生素杂志,2017,Issue.2

关键词:倍半萜;Albaflavenone;Strepsesquitriol;Epi-isozizaene合酶;

资源类型:中文期刊论文

6. Activation of a Cryptic Gene Cluster in Lysobacter enzymogenes Reveals a Module/Domain Portable Mechanism of Nonribosomal Peptide Synthetases in the Biosynthesis of Pyrrolopyrazines SCIE SCOPUS PubMed

作者:Li, SR;Wu, XL;Zhang, LM;Shen, YM;Du, LC

作者机构:[Li, Shanren; Shen, Yuemao; Du, Liangcheng] Shandong Univ, Coll Life Sci, State Key Lab Microbial Technol, Jinan 250100, Shandong, Peoples R China.; [Li, Shanren; Wu, Xiuli; Du, Liangcheng] Univ Nebraska Lincoln, Dept Chem, Lincoln, NE 68588 USA.; [Zhang, Limei] Univ Nebraska Lincoln, Dept Biochem, Lincoln, NE 68588 USA.; [Wu, Xiuli] Ningxia Med Univ, Coll Pharm, Yinchuan 750004, Peoples R China.

来源:ORGANIC LETTERS,2017,Vol.19,Issue.19,5010-5013

最新影响因子:6.579

资源类型:外文期刊论文

WOS被引频次: 1

7. Indole-Induced Reversion of Intrinsic Multiantibiotic Resistance in Lysobacter enzymogenes EI SCIE SCOPUS PubMed

作者:Han, Y;Wang, Y;Yu, YM;Chen, HT;Shen, YM;Du, LC

作者机构:[Han, Yong; Shen, Yuemao; Du, Liangcheng] Shandong Univ, Coll Life Sci, State Key Lab Microbial Technol, Jinan, Shandong, Peoples R China.; [Han, Yong; Shen, Yuemao; Du, Liangcheng] Shandong Univ, Coll Life Sci, Key Lab Chem Biol, Jinan, Shandong, Peoples R China.; [Han, Yong; Shen, Yuemao; Du, Liangcheng] Shandong Univ, Sch Pharmaceut Sci, Jinan, Shandong, Peoples R China.; [Han, Yong; Wang, Yan; Chen, Haotong; Du, Liangcheng] Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA.; [Wang, Yan; Yu, Yameng] Ocean Univ China, Coll Marine Life Sci, Qingdao, Peoples R China.

来源:APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2017,Vol.83,Issue.17

最新影响因子:3.807

资源类型:外文期刊论文

WOS被引频次: 0

8. Cytotoxic Polyketides with an Oxygen-Bridged Cyclooctadiene Core Skeleton from the Mangrove Endophytic Fungus Phomosis sp A818 SCIE SCOPUS PubMed

作者:Zhang, W;Zhao, BB;Du, LC;Shen, YM

作者机构:[Zhang, Wei] Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Shandong Prov Key Lab Synthet Biol, Qingdao 266101, Peoples R China.; [Zhang, Wei; Du, Liangcheng] Univ Nebraska Lincoln, Dept Chem, Lincoln, NE 68588 USA.; [Zhao, Baobing; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Chem Biol, Jinan 250012, Shandong, Peoples R China.

来源:MOLECULES,2017,Vol.22,Issue.9

最新影响因子:2.861

资源类型:外文期刊论文

WOS被引频次: 0

9. Neoansamycins from Streptomyces sp LZ35 EI SCIE SCOPUS

作者:Liu, MJ;Lu, CH;Tang, RC;Li, SR;Wang, HX;Shen, YM

作者机构:[Liu, Mengyujie; Lu, Chunhua; Li, Shanren; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Key Lab Chem Biol, Minist Educ, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Tang, Ruocong; Wang, Haoxin; Shen, Yuemao] Shandong Univ, State Key Lab Microbial Technol, Jinan 250100, Shandong, Peoples R China.

来源:RSC ADVANCES,2017,Vol.7,Issue.56,35460-35465

最新影响因子:3.108

资源类型:外文期刊论文

WOS被引频次: 0

10. Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029 SCIE SCOPUS PubMed

作者:Bian, XY;Tang, B;Yu, YC;Tu, Q;Gross, F;Wang, HL;Li, AY;Shen, YM;Li, YZ;Stewart, AF;Zhao, GP;Ding, XM;Muller, R;Zhang, YM

作者机构:[Bian, Xiaoying; Wang, Hailong; Li, Aiying; Shen, Yuemao; Li, Yue-zhong; Stewart, A. Francis; Ding, Xiaoming] Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol, Helmholtz Inst Biotechnol, Qingdao 266235, Peoples R China.; [Bian, Xiaoying; Tu, Qiang; Mueller, Rolf] Helmholtz Ctr Infect Res, Helmholtz Inst Pharmaceut Res, Dept Microbial Nat Prod, D-66123 Saarbrucken, Germany.; [Bian, Xiaoying; Tu, Qiang; Mueller, Rolf] Saarland Univ, D-66123 Saarbrucken, Germany.; [Tang, Biao; Yu, Yucong; Zhao, Guoping; Ding, Xiaoming] Fudan Univ, Sch Life Sci, Dept Microbiol, Collaborat Innovat Ctr Genet & Dev,State Key Lab, Shanghai 200433, Peoples R China.; [Gross, Frank; Stewart, A. Francis] Tech Univ Dresden, Ctr Biotechnol, Genom, D-01062 Dresden, Germany.; [Zhao, Guoping; Ding, Xiaoming] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Plant Physiol & Ecol, CAS Key Lab Synthet Biol, Shanghai 200032, Peoples R China.

来源:ACS CHEMICAL BIOLOGY,2017,Vol.12,Issue.7,1805-1812

最新影响因子:4.995

资源类型:外文期刊论文

WOS被引频次: 0

11. Characterization of the flavoenzyme XiaK as an N-hydroxylase and implications in indolosesquiterpene diversification EI SCIE SCOPUS PubMed

作者:Zhang, QB;Li, HX;Yu, L;Sun, Y;Zhu, YG;Zhu, HN;Zhang, LP;Li, SM;Shen, YM;Tian, CL;Li, A;Liu, HW;Zhang, CS

作者机构:[Zhang, Qingbo; Li, Huixian; Zhu, Yiguang; Zhu, Hanning; Zhang, Liping; Zhang, Changsheng] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, South China Sea Inst Oceanol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China.; [Li, Huixian] Sun Yat Sen Univ, South China Sea Resource Exploitat & Protect Coll, Sch Marine Sci, Inst Marine Nat Prod, 135 West Xingang Rd, Guangzhou 510006, Guangdong, Peoples R China.; [Yu, Lu; Tian, Changlin; Li, Ang] Univ Sci & Technol China, Sch Life Sci, Hefei Natl Lab Microscale Phys Sci, Hefei 230027, Peoples R China.; [Yu, Lu] Chinese Acad Sci, High Magnet Field Lab, Hefei 230031, Peoples R China.; [Sun, Yu] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China.; [Li, Shu-Ming] Philipps Univ Marburg, Inst Pharmazeut Biol & Biotechnol, Deutschhausstr 17a, D-35037 Marburg, Germany.; [Shen, Yuemao] Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol, Jinan 250100, Peoples R China.; [Liu, Hung-Wen] Univ Texas Austin, Dept Chem, Coll Pharm, Div Chem Biol & Med Chem, Austin, TX 78712 USA.

来源:CHEMICAL SCIENCE,2017,Vol.8,Issue.7,5067-5077

最新影响因子:8.668

资源类型:外文期刊论文

WOS被引频次: 1

12. Bisindolylmaleimide alkaloid BMA-155Cl induces autophagy and apoptosis in human hepatocarcinoma HepG-2 cells through the NF-kappa B p65 pathway SCIE SCOPUS PubMed

作者:Sun, XA;Li, L;Ma, HG;Sun, P;Wang, QL;Zhang, TT;Shen, YM;Zhu, WM;Li, X

作者机构:[Sun, Xiao; Li, Lin; Sun, Pu; Wang, Qi-lin; Zhang, Ting-ting; Li, Xia] Shandong Univ, Sch Ocean, Weihai 264209, Peoples R China.; [Ma, Hong-guang; Zhu, Wei-ming] Ocean Univ China, Sch Med & Pharm, Qingdao 266000, Peoples R China.; [Sun, Xiao; Li, Lin; Shen, Yue-mao; Li, Xia] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Peoples R China.

来源:ACTA PHARMACOLOGICA SINICA,2017,Vol.38,Issue.4,524-538

最新影响因子:3.223

资源类型:外文期刊论文

WOS被引频次: 0

13. 4-Hydroxybenzoic acid is a diffusible factor that connects metabolic shikimate pathway to the biosynthesis of a unique antifungal metabolite in Lysobacter enzymogenes SCIE SCOPUS PubMed

作者:Su, ZH;Chen, HF;Wang, P;Tombosa, S;Du, LC;Han, Y;Shen, YM;Qian, GL;Liu, FQ

作者机构:[Su, Zhenhe; Chen, Hongfu; Wang, Ping; Qian, Guoliang; Liu, Fengquan] Nanjing Agr Univ, Minist Educ, Coll Plant Protect, Dept Plant Pathol,Key Lab Integrated Management C, Nanjing 210095, Jiangsu, Peoples R China.; [Liu, Fengquan] Jiangsu Acad Agr Sci, Inst Plant Protect, Dept Plant Pathol, Nanjing 210014, Jiangsu, Peoples R China.; [Tombosa, Simon; Du, Liangcheng; Han, Yong] Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA.; [Han, Yong; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod, Key Lab Chem Biol, Jinan 250100, Peoples R China.

来源:MOLECULAR MICROBIOLOGY,2017,Vol.104,Issue.1,163-178

最新影响因子:3.898

资源类型:外文期刊论文

WOS被引频次: 3

14. Mycoepoxydiene suppresses HeLa cell growth by inhibiting glycolysis and the pentose phosphate pathway EI SCIE SCOPUS PubMed

作者:Jin, KH;Li, L;Sun, XH;Xu, QY;Song, SY;Shen, YM;Deng, XM

作者机构:[Jin, Kehua; Li, Li; Sun, Xihuan; Xu, Qingyan; Song, Siyang; Deng, Xianming] Xiamen Univ, Sch Life Sci, Innovat Ctr Cell Signaling Network, State Key Lab Cellular Stress Biol, Xiamen, Fujian, Peoples R China.; [Jin, Kehua; Li, Li; Sun, Xihuan; Xu, Qingyan; Song, Siyang; Deng, Xianming] Xiamen Univ, State Prov Joint Engn Lab Targeted Drugs Nat Prod, Xiamen, Fujian, Peoples R China.; [Jin, Kehua] Hubei Univ Sci & Technol, Sch Basic Med Sci, Xianning, Hubei, Peoples R China.; [Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Jinan, Shandong, Peoples R China.

来源:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2017,Vol.101,Issue.10,4201-4213

最新影响因子:3.42

资源类型:外文期刊论文

WOS被引频次: 1

15. Nam7 Hydroxylase Is Responsible for the Formation of the Naphthalenic Ring in the Biosynthesis of Neoansamycins SCIE SCOPUS PubMed

作者:Zhang, JL;Li, SR;Wu, XK;Guo, ZX;Lu, CH;Shen, YM

作者机构:[Zhang, Juanli; Li, Shanren; Wu, Xingkang; Guo, Zhixing; Lu, Chunhua; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Chem Biol, Jinan 250012, Shandong, Peoples R China.; [Zhang, Juanli] Fourth Mil Med Univ, Xijing Hosp, Dept Pharm, Changle West St 15, Xian 710032, Shaanxi, Peoples R China.; [Shen, Yuemao] Shandong Univ, State Key Lab Microbial Technol, Jinan 250100, Shandong, Peoples R China.

来源:ORGANIC LETTERS,2017,Vol.19,Issue.9,2442-2445

最新影响因子:6.579

资源类型:外文期刊论文

WOS被引频次: 2

16. Two novel cyclic hexapeptides from the genetically engineered Actinosynnema pretiosum EI SCIE SCOPUS PubMed

作者:Lu, CH;Xie, F;Shan, C;Shen, YM

作者机构:[Lu, Chunhua; Xie, Fei; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Key Lab Chem Biol, Minist Educ, Jinan 250012, Shandong, Peoples R China.; [Shan, Chuan] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China.

来源:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2017,Vol.101,Issue.6,2273-2279

最新影响因子:3.42

资源类型:外文期刊论文

WOS被引频次: 0

17. Ansavaricins F-I, new DNA topoisomerase inhibitors produced by Streptomyces sp S012 EI SCIE SCOPUS

作者:Zhang, ZQ;Wu, XK;Song, RT;Zhang, JL;Wang, HX;Zhu, J;Lu, CH;Shen, YM

作者机构:[Zhang, Zhiqiang; Wu, Xingkang; Lu, Chunhua; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Chem Biol, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Song, Rentai; Wang, Haoxin; Zhu, Jing; Shen, Yuemao] Shandong Univ, State Key Lab Microbial Technol, 27 South Shanda Rd, Jinan 250100, Shandong, Peoples R China.; [Zhang, Juanli] Fourth Mil Med Univ, Xijing Hosp, Dept Pharm, Changle West St 15, Xian 710032, Shaanxi, Peoples R China.

来源:RSC ADVANCES,2017,Vol.7,Issue.24,14857-14867

最新影响因子:3.108

资源类型:外文期刊论文

WOS被引频次: 2

18. Ansavaricins A-E: five new streptovaricin derivatives from Streptomyces sp S012 EI SCIE SCOPUS

作者:Zhang, ZQ;Zhang, JL;Song, RT;Guo, ZX;Wang, HX;Zhu, J;Lu, CH;Shen, Y

作者机构:[Zhang, Zhiqiang; Guo, Zhixing; Lu, Chunhua; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Chem Biol, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Zhang, Juanli] Fourth Mil Med Univ, Xijing Hosp, Dept Pharm, Changle West St 15, Xian 710032, Shaanxi, Peoples R China.; [Song, Rentai; Wang, Haoxin; Zhu, Jing; Shen, Yuemao] Shandong Univ, State Key Lab Microbial Technol, 27 South Shanda Rd, Jinan 250100, Shandong, Peoples R China.

来源:RSC ADVANCES,2017,Vol.7,Issue.10,5684-5693

最新影响因子:3.108

资源类型:外文期刊论文

WOS被引频次: 3

19. New diketopiperazine derivatives with cytotoxicity from Nocardiopsis sp YIM M13066 SCIE SCOPUS PubMed

作者:Sun, MW;Chen, XT;Li, WJ;Lu, CH;Shen, YM

作者机构:[Sun, Mingwei; Lu, Chunhua; Shen, Yuemao] Shandong Univ, Sch Pharmaceut Sci, Key Lab Chem Biol, Minist Educ, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Chen, Xiaotong] Shandong Univ, Sch Med, Dept Immunol, Jinan, Peoples R China.; [Li, Wenjun] Sun Yat Sen Univ, Coll Ecol & Evolut, State Key Lab Biocontrol, Guangzhou, Guangdong, Peoples R China.; [Li, Wenjun] Sun Yat Sen Univ, Coll Ecol & Evolut, Guangdong Prov Key Lab Plant Resources, Guangzhou, Guangdong, Peoples R China.

来源:JOURNAL OF ANTIBIOTICS,2017,Vol.70,Issue.6,795-797

最新影响因子:2.237

资源类型:外文期刊论文

WOS被引频次: 0

20. 海南红树林根际糖多胞菌菌株YIM M13568的红霉素类抗生素的分离和鉴定 万方 CSCD 维普 知网

作者:孙明伟;丁艳娇;鲁春华;沈月毛

作者机构:[孙明伟]山东大学药学院, 化学生物学教育部重点实验室, 济南, 山东 250012, 中国;[丁艳娇]山东大学药学院, 化学生物学教育部重点实验室, 济南, 山东 250012, 中国;[鲁春华]山东大学药学院, 化学生物学教育部重点实验室, 济南, 山东 250012, 中国;[沈月毛]山东大学药学院, 化学生物学教育部重点实验室, 济南, 山东 250012, 中国.

来源:中国抗生素杂志,2017,Vol.42,Issue.4,s26-s30

关键词:糖多胞菌; 红树林根际; 红霉素家族抗生素; 抗菌活性

资源类型:中文期刊论文

WOS被引频次: 0

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