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1. N9位芳基取代嘌呤-8-酮类衍生物的合成及抗肿瘤活性 EI CSCD SCIE

作者:吕明君; 李雯; 杨新颖; 方浩

作者机构:[吕明君]山东大学药学院药物化学教研室, 济南, 山东 250012, 中国;[李雯]山东大学药学院药物化学教研室, 济南, 山东 250012, 中国;[杨新颖]山东大学药学院药物化学教研室, 济南, 山东 250012, 中国;[方浩]山东大学药学院药物化学教研室, 济南, 山东 250012, 中国.

来源:高等学校化学学报,CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2019,Vol.40,Issue.2,254-261

资源类型:期刊论文

WOS:000468451500007

2. Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties SCOPUS

作者:Wu J.-D.; Cui Y.-J.; Zhou Y.-G.; Tang L.-Q.; Zhang C.-M.; Liu Z.-P.

作者机构:[Wu, J.-D] Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China;[ Cui, Y.-J] Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China;[ Zhou, Y.-G] Actpharma Co. Ltd., Shanghe Economic Development Zone of Shandong Province, Shanghe, 251600, China;[ Tang, L.-Q] Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China;[ Zhang, C.-M] Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China;[ Liu, Z.-P] Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China

来源:Investigational New Drugs,2019

资源类型:期刊论文

3. Nanoemulsion prepared by homogenizer : The CFD model research SCOPUS SCIE

作者:Jiang, Bo; Shi, Yanbin; Lin, Guimei; Kong, Deyin; Du, Jian

作者机构:[Jiang, Bo; Shi, Yanbin; Kong, Deyin; Du, Jian] Qilu Univ Technol, Shandong Acad Sci, Sch Mech & Automot Engn, 3501 Daxue Rd, Jinan 250353, Shandong, Peoples R China.; [Lin, Guimei] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China.

来源:JOURNAL OF FOOD ENGINEERING,2019,Vol.241,105-115

资源类型:期刊论文

WOS:000447581200013

4. Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2 V617F against myeloproliferative neoplasms SCOPUS

作者:Hu M.; Xu C.; Yang C.; Zuo H.; Chen C.; Zhang D.; Shi G.; Wang W.; Shi J.; Zhang T.

作者机构:[Hu, M] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Xu, C] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Yang, C] Department of Blood Transfusion, General Hospital, PLA Rocket Force, Beijing, 100088, China;[ Zuo, H] Department of Hematology, 307 Hospital of the PLA, Beijing, 100071, China;[ Chen, C] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Zhang, D] Department of Pharmacy, China-Japan Friendship Hospital, Beijing, 100029, China;[ Shi, G] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Wang, W] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Shi, J] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China;[ Zhang, T] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100050, China, School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China

来源:Journal of Experimental and Clinical Cancer Research,2019,Vol.38,Issue.1

资源类型:期刊论文

5. The roles and signaling pathways of prolyl-4-hydroxylase 2 in the tumor microenvironment SCOPUS SCIE

作者:Li, Anqi; Zhang, Yu; Wang, Zuojun; Dong, Hailing; Fu, Nange; Han, Xiuzhen

作者机构:[Li, Anqi; Zhang, Yu; Dong, Hailing; Fu, Nange; Han, Xiuzhen] Shandong Univ, Sch Pharmaceut Sci, Dept Pharmacol, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Wang, Zuojun] Linqu Country Peoples Hosp, Dept Pharm, 438 Shanwang Rd, Linqu 262600, Peoples R China.

来源:CHEMICO-BIOLOGICAL INTERACTIONS,2019,Vol.303,40-49

资源类型:期刊论文

WOS:000462156600007

6. PCSK9 Inhibitors: Novel Therapeutic Strategies for Lowering LDL-Cholesterol SCOPUS SCIE

作者:Wang, Yan; Liu, Zhao-Peng

作者机构:[Wang, Yan; Liu, Zhao-Peng] Shandong Univ, Sch Pharmaceut Sci, Key Lab Chem Biol, Inst Med Chem,Minist Educ, Jinan 250012, Shandong, Peoples R China.

来源:MINI-REVIEWS IN MEDICINAL CHEMISTRY,2019,Vol.19,Issue.2,165-176

WOS被引数:2

资源类型:期刊论文

WOS:000457099300006

7. Yifei Tongluo, a Chinese Herbal Formula, Suppresses Tumor Growth and Metastasis and Exerts Immunomodulatory Effect in Lewis Lung Carcinoma Mice SCOPUS SCIE

作者:Qi, Qiuchen; Hou, Yanhong; Li, Ang; Sun, Yueyue; Li, Siying; Zhao, Zhongxi

作者机构:[Qi, Qiuchen; Hou, Yanhong; Li, Ang; Sun, Yueyue; Zhao, Zhongxi] Shandong Univ, Sch Pharmaceut Sci, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Li, Siying] Shandong Univ, Sch Basic Med Sci, Dept Pathol & Pathophysiol, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Zhao, Zhongxi] Shandong Acad Pharmaceut Sci, Shandong Prov Key Lab Mucosal & Transdermal Drug, 989 Xinluo St, Jinan 250101, Shandong, Peoples R China.; [Zhao, Zhongxi] Shandong Engn & Technol Res Ctr Jujube Food & Dru, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.

来源:MOLECULES,2019,Vol.24,Issue.4

资源类型:期刊论文

WOS:000460805900077

8. Protective effects of ethyl gallate on H2O2-induced mitochondrial dysfunction in PC12 cells SCOPUS SCIE

作者:Chen, Lan; Wu, Xuewei; Shen, Tao; Wang, Xiaoning; Wang, Shuqi; Wang, Jinxia; Ren, Dongmei

作者机构:[Chen, Lan; Wu, Xuewei; Shen, Tao; Wang, Xiaoning; Wang, Shuqi; Wang, Jinxia; Ren, Dongmei] Shandong Univ, Sch Pharmaceut Sci, Minist Educ, Key Lab Chem Biol, 44 Wenhuaxi Rd, Jinan 250012, Shandong, Peoples R China.

来源:METABOLIC BRAIN DISEASE,2019,Vol.34,Issue.2,545-555

资源类型:期刊论文

WOS:000462156500016

9. Redox-Sensitive Prodrug Molecules Meet Graphene Oxide: An Efficient Graphene Oxide-Based Nanovehicle toward Cancer Therapy SCOPUS SCIE

作者:Ma, Naxin; Song, Aixin; Li, Zhonghao; Luan, Yuxia

作者机构:[Ma, Naxin; Luan, Yuxia] Shandong Univ, Minist Educ, Key Lab Chem Biol, Sch Pharmaceut Sci, 44 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.; [Song, Aixin; Li, Zhonghao] Shandong Univ, Minist Educ, Key Lab Colloid & Interface Chem, Jinan 250100, Shandong, Peoples R China.

来源:ACS BIOMATERIALS SCIENCE & ENGINEERING,2019,Vol.5,Issue.3,1384-1391

资源类型:期刊论文

WOS:000461270200022

10. Induced production of steroids by co-cultivation of two endophytes from Mahonia fortunei SCOPUS SCIE

作者:Wang, Zi-Ru; Li, Gang; Ji, Li-Xia; Wang, Hang-Hang; Gao, Han; Peng, Xiao-Ping; Lou, Hong-Xiang

作者机构:[Wang, Zi-Ru; Li, Gang; Ji, Li-Xia; Wang, Hang-Hang; Gao, Han; Peng, Xiao-Ping; Lou, Hong-Xiang] Qingdao Univ, Sch Pharm, Dept Nat Med Chem & Pharmacognosy, Qingdao 266021, Shandong, Peoples R China.; [Lou, Hong-Xiang] Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Key Lab Chem Biol,Minist Educ, Jinan 250012, Shandong, Peoples R China.

来源:STEROIDS,2019,Vol.145,1-4

资源类型:期刊论文

WOS:000463131400001

11. CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway SCOPUS SCIE

作者:Zheng, Mei; Zhou, Qin; Liu, Xingguang; Wang, Chengze; Liu, Gangli

作者机构:[Zheng, Mei] Shandong Univ, Qianfoshan Hosp, Dept Tradit Chinese Med, Jinan 250014, Shandong, Peoples R China.; [Zhou, Qin; Liu, Xingguang; Wang, Chengze; Liu, Gangli] Shandong Univ, Shandong Prov Key Lab Oral Tissue Regenerat, Sch Stomatol, 44-1 West Wenhua Rd, Jinan 250012, Shandong, Peoples R China.

来源:ONCOLOGY REPORTS,2019,Vol.41,Issue.3,1531-1538

资源类型:期刊论文

WOS:000459552700009

12. Discovery of monoamine oxidase inhibitors by medicinal chemistry approaches SCOPUS SCIE

作者:Hong, Renyuan; Li, Xun

作者机构:[Hong, Renyuan; Li, Xun] Shandong Univ, Sch Pharmaceut Sci, Dept Med Chem, Key Lab Chem Biol,Minist Educ, 44 West Culture Rd, Jinan 250012, Shandong, Peoples R China.

来源:MEDCHEMCOMM,2019,Vol.10,Issue.1,10-25

资源类型:期刊论文

WOS:000457343000001

13. 唾液酸苷酶的催化机理及水解与合成寡糖进展 CSCD

作者:郭龙成; 马忠轩; 卢丽丽; 肖敏

作者机构:[郭龙成]山东大学, 国家糖工程技术研究中心;;微生物技术国家重点实验室;;山东省糖化学生物学省级重点实验室, 青岛, 山东 266237, 中国;[马忠轩]山东大学, 国家糖工程技术研究中心;;微生物技术国家重点实验室;;山东省糖化学生物学省级重点实验室, 青岛, 山东 266237, 中国;[肖敏]山东大学, 国家糖工程技术研究中心;;微生物技术国家重点实验室;;山东省糖化学生物学省级重点实验室, 青岛, 山东 266237, 中国;[卢丽丽]山东大学;;华中科技大学同济医学院药学院, 国家糖工程技术研究中心;;微生物技术国家重点实验室;;山东省糖化学生物学省级重点实验室;;, 青岛;;武汉, ;; 266237;;430074.

来源:生物化学与生物物理进展,Progress in Biochemistry and Biophysics,2019,Vol.46,Issue.2,181-192

资源类型:期刊论文

14. Multiple sealed primers-mediated rolling circle amplification strategy for sensitive and specific detection of DNA methyltransferase activity EI SCOPUS SCIE

作者:Xu, Xiaowen; Wang, Lei; Li, Xia; Cui, Wanling; Jiang, Wei

作者机构:[Xu, Xiaowen; Cui, Wanling; Jiang, Wei] Shandong Univ, Sch Chem & Chem Engn, Educ Minist, Key Lab Colloid & Interface Chem, Jinan 250100, Shandong, Peoples R China.; [Li, Xia] Liaocheng Univ, Dept Chem, Liaocheng 252059, Peoples R China.; [Wang, Lei] Shandong Univ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China.

来源:TALANTA,2019,Vol.194,282-288

资源类型:期刊论文

WOS:000456899700037

15. Synthesis, characterization, and anticancer activities evaluation of compounds derived from 3,4-dihydropyrimidin-2(1H)-one SCOPUS

作者:Liu Y.; Liu J.; Zhang R.; Guo Y.; Wang H.; Meng Q.; Sun Y.; Liu Z.

作者机构:[Liu, Y] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Liu, J] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Zhang, R] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Guo, Y] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Wang, H] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Meng, Q] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China;[ Sun, Y] Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, CA 95817, United States;[ Liu, Z] School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs, Universities of Shandong, Yantai University, Yantai, 264005, China

来源:Molecules,2019

资源类型:期刊论文

16. Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I SCOPUS SCIE

作者:Kang, Dongwei; Wang, Zhao; Chen, Meng; Feng, Da; Wu, Gaochan; Zhou, Zhongxia; Jing, Lanlan; Zuo, Xiaofang; Jiang, Xiangyi; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Zhan, Peng; Liu, Xinyong

作者机构:[Kang, Dongwei; Wang, Zhao; Feng, Da; Wu, Gaochan; Zhou, Zhongxia; Jing, Lanlan; Zuo, Xiaofang; Jiang, Xiangyi; Zhan, Peng; Liu, Xinyong] Shandong Univ, Dept Med Chem, Key Lab Chem Biol, Minist Educ,Sch Pharmaceut Sci, Jinan, Shandong, Peoples R China.; [Chen, Meng] Shandong Ctr Dis Control & Prevent, Jinan, Shandong, Peoples R China.; [Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe] Katholieke Univ Leuven, Rega Inst Med Res, Leuven, Belgium.

来源:CHEMICAL BIOLOGY & DRUG DESIGN,2019,Vol.93,Issue.4,430-437

资源类型:期刊论文

WOS:000462929000004

17. Drug Screening and Discovery Strategies at Nanoscale Morphology using Structured Illumination Microscopy CPCI-S SCIE

作者:Shao, Xintian; Chen, Qixin; Ling, Peixue; Diao, Jiajie

作者机构:[Shao, Xintian; Chen, Qixin; Ling, Peixue] Shandong Univ, Sch Pharmaceut Sci, Jinan, Shandong, Peoples R China.; [Shao, Xintian; Chen, Qixin; Diao, Jiajie] Univ Cincinnati, Coll Med, Dept Canc Biol, Cincinnati, OH USA.

会议名称:63rd Annual Meeting of the Biophysical-Society

会议日期:MAR 02-06, 2019

来源:BIOPHYSICAL JOURNAL,2019,Vol.116,Issue.3,267A-267A

资源类型:会议论文

WOS:000460779801333

18. 中文版MMAS-8评价心血管慢病患者用药依从性的信效度分析与实践

作者:陈强;曲珊珊;黄欣;

作者机构:[陈强]山东大学药学院,中国.;[曲珊珊]淄博矿业集团有限责任公司中心医院药学部,中国.;[黄欣]山东省千佛山医院药学部,中国

来源:中国药房,2019,Issue.02,268-271

资源类型:期刊论文

19. The identification and functional characterization of three liverwort class I O-methyltransferases SCOPUS SCIE

作者:Liu, Hui; Xu, Rui-Xue; Zhang, Xiao-Shuang; Zhu, Ting-Ting; Lou, Hong-Xiang; Cheng, Ai-Xia

作者机构:[Liu, Hui; Xu, Rui-Xue; Zhang, Xiao-Shuang; Zhu, Ting-Ting; Lou, Hong-Xiang; Cheng, Ai-Xia] Shandong Univ, Key Lab Chem Biol Nat Prod, Minist Educ, Sch Pharmaceut Sci, Jinan 250012, Shandong, Peoples R China.

来源:PHYTOCHEMISTRY,2019,Vol.159,190-198

资源类型:期刊论文

WOS:000458710000020

20. Corrigendum to “Methylallyl sulfone attenuates inflammation, oxidative stress and lung injury induced by cigarette smoke extract in mice and RAW264.7 cells” (International Immunopharmacology (2018) 59 (369–374), (S1567576918301796), (10.1016/j.intimp.2018.04.028)) SCOPUS

作者:Li A.; Liu Y.; Zhu X.; Sun X.; Feng X.; Li D.; Zhang J.; Zhu M.; Zhao Z.

作者机构:[Li, A] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China;[ Liu, Y] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China;[ Zhu, X] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China;[ Sun, X] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China;[ Feng, X] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China;[ Li, D] Shandong Provincial Key Laboratory of Mucosal and Transdermal Drug Delivery Technologies, Shandong Freda Pharmaceutical Group Co., Ltd., 888 Xinluo Street, Jinan, Shandong 250101, China;[ Zhang, J] Shandong Provincial Key Laboratory of Mucosal and Transdermal Drug Delivery Technologies, Shandong Freda Pharmaceutical Group Co., Ltd., 888 Xinluo Street, Jinan, Shandong 250101, China;[ Zhu, M] Shandong Provincial Key Laboratory of Mucosal and Transdermal Drug Delivery Technologies, Shandong Freda Pharmaceutical Group Co., Ltd., 888 Xinluo Street, Jinan, Shandong 250101, China;[ Zhao, Z] School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China, Shandong Engineering & Technology Research Center for Jujube Food and Drug, 44 West Wenhua Road, Jinan, Shandong 250012, China, Shandong Provincial Key Laboratory of Mucosal and Transdermal Drug Delivery Technologies, Shandong Freda Pharmaceutical Group Co., Ltd., 888 Xinluo Street, Jinan, Shandong 250101, China

来源:International Immunopharmacology,2019

资源类型:期刊论文

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